USD per year
The Role
Output has built a biological reasoning model that understands biology at the scale and complexity life actually operates. Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously impossible. We're already generating therapies that traditional approaches cannot reach. The hardest problems in both AI and biology are being solved here, and there is room for you to own one. Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator. You own the feedback loop between Output's models and the lab. You go deep into specific biological problems, translate what the biology requires into priorities for data and modeling, and manage through CRO partners the experimental cycle that validates model outputs and generates new data. You will own the active learning cycle between Output's models and experimental validation: designing experiments, managing CRO partners for synthesis and testing, interpreting results, and feeding them back to improve the models You will dive into specific biological problem areas, developing the expertise needed to translate nuanced biological requirements into priorities for data construction, modeling, and evaluation You will manage CRO relationships for peptide and molecular synthesis, biological assays, and experimental testing, designing each campaign to generate maximally informative data You will collaborate with the engineering team to design and build biology-specific agent skills and workflows, encoding your biological expertise into tools that automate experimental decision-making You will work closely with the model and data teams, identifying biological phenomena the models should be sensitive to and ensuring that experimental findings shape what and how the models learn You will stay current with biological literature and experimental methods, continuously identifying new biological problems and translating them into opportunities for model development
About You
You have a PhD in computational biology, biophysics, structural biology, molecular biology, or a related biological field with 3+ years of post-doctoral or industry research experience.
Values
- Heart: Ownership culture; everyone takes responsibility for their work.
- Excellence: High standards; focus on quality results.
- Practicality: Results-oriented; pragmatic problem solving.
- Honesty: Open communication; transparency.
- Fun: Engaging workplace; supportive environment.
What We Offer
- Encouragement of new ideas & creativity.
- Healthy feedback environment with leadership support.
- Ownership of day-to-day management focused on milestones.
- Competitive salary & equity in a well-funded startup.
- Excellent medical/dental/vision coverage.
Output Biosciences is pioneering Biologically-Aware Generative AI to understand complex biological systems. They build Large Biological Models that generate breakthrough medicines using a generative AI architecture capable of handling extremely long, nonlinear, fragmented, and high dimensional biological data. Their team includes repeat founders of AI-driven biotech startups, physicians, researchers in computational systems biology and nonlinear dynamics, and experienced biotech executives and investors.
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