Senior Scientist, Computational Biology & Data Infrastructure

Location

Brooklyn

Employment Type

Full time

Location Type

On-site

Department

Science

Compensation

$132.5K – $160K • Offers Equity • 100% fully-covered, best-in-class medical, vision, and dental insurance for yourself (and 95% for your spouse/family) + other excellent benefits

OVERVIEW At Kingdom, we’ve pioneered Superculture® ingredients: an entirely new class of clinically-validated postbiotics that target the root causes of unmet pet health needs. We’re actively selling Superculture® Pet Oral and Superculture® Pet Immune to pet food and supplement brands, and will be launching our first Superculture ingredient for humans later this year. We're looking for a high-performing Senior Scientist, Computational Biology & Data Infrastructure & Data Infrastructure, to join our small but mighty team. This is an AI-native science role: you'll own the computational backbone of Kingdom's research (the microbial genomics and AI-compatible data infrastructure that every wet-lab program depends on) and ship custom and integrated LLM tooling to automate and accelerate our work. We want a PhD-level computational biologist (or related area) who applies rigorous scientific judgment to genomic analysis, biobank strategy, and statistical methods, and is equally excited to build the systems that let everyone move faster. Fundamentally, this is a science role, with success measured by the integrity of our data, the insights our data infrastructure unlocks, and the AI tooling we deploy across our scientific platform. This is a full-time, in-person role at our headquarters in Brooklyn, NY. We founded Kingdom in 2019 to cultivate healthier living with natural microbes, and have raised $35M+ in venture funding from top investors. Less than a year in market, our ingredients are already powering dozens of products from leading pet brands, with overwhelmingly positive customer reception. 1 out of 3 product launches using our ingredients have earned a #1 New Release on Amazon, and 9 out of 10 of our customers are launching additional products with us. Our core technical edge is our scientific platform, which spans ingredient discovery, clinical trials, and manufacturing scale-up. RESPONSIBILITIES In this role, you’ll report to the Senior Scientific Director, and will work closely with our science team & co-founders to: Own genomic analyses and biobank strategy:

Run computational genomic safety analyses and author the supporting reports that underpin our regulatory and customer-facing safety documentation
Maintain the whole-genome sequencing pipeline: assembly of incoming sequencing data, linkage of genomes to strain records, and curation of best-available assemblies for downstream use
Own and operate the strain dereplication pipeline, advancing isolated colonies from primary 16S/ITS screening through unique-strain identification and entry into the biobank
Design and curate screening plates for downstream functional assays, including layout, strain selection, and verification of taxonomy and safety annotations

Build and own Kingdom’s AI-compatible scientific data infrastructure:

Build AI-compatible data infrastructure for Kingdom that captures, stores,and analyzes data across a variety of modalities
Develop and apply statistical and computational methods to power biological insightsand support wet-lab workflows,includi ng experimental design ,metric developmentand validation,and method onboarding,powered with new AI/agentic tools
Maintain the integrity of the strain database backend: tube tracking,naming conventions,and audits of our physical inventoryand pipeline data to identify anomalies
Model complex ,interrelated scientific entities(samples ,experiments,runs ,results ,physical inventory) into a coherent schemaand ontologythe team can work in
Scope ,build,and shipthe data processing ,analysis,and metrics that give new assays clear ,validated benchmarks

COMPETENCIES & QUALIFICATIONS

PhD (or equivalent depth) in computational biology,bioinformatics,microbial genomics ,or a related quantitative life-sciences field; ~1-3 years post-PhD
Domain depth in microbial genomics: whole-genome sequencing ,16S/ITS amplicon analysis,dereplication,taxonomy,and genomic safety annotation
Strong knowledge of statisticsand quantitative methods
Advanced coding literacy: expert-level Python or R ,proficiency with SQL ,fluency with containerizationfor reproducible pipelines ,comfort building tools that interactwith third-party APIs,and strong code-quality practices(version control ,testing ,code review)
Experience designingand maintaining bio-data infrastructure: proficiency modeling complex interrelated entitiesand comfort establishingand communicating an ontology
AI-native: daily Claude Code or equivalent use,prompt fluency ,comfort rebuilding research cadence around agentic tools ,with experience building tooling around your own research
High agency: self-starter who identifies pain points ,proposes a planand solution,and drives their own learning
Builder mentality: comfortable with building a first versionof a tool fast,and iterating to improve
Bias to actionable output: instinctto package findings into something concrete that unblocks decisionsand moves thenext step forward
Clearandeffective writtenand verbal communication

WHY JOIN KINGDOM

Meaningful work: contribute to a category-defining biotech company at the frontierof postbiotic science.
Growthand learning: Kingdom’s scientific AIand data-infrastructure functionis still being defined,you’ll have real influence over what it becomes.Because therole supports every wet-lab program,you’ll gain broader exposureto microbial scienceand ingredient development.
Ownershipand autonomy: inherit a functioning biobank infrastructureanda working genomic-safety pipeline; AIdata infrastructure: substantive work from day onewith substantial latitude to shapethe platform.Earlyandsustained exposureto the Chief Science Officer.
Teamand culture: small but mighty team that's high-performing ,kind,and AI-native.

OUR VALUES

Solve from first principles . We havea deep-seated curiosity aboutthe most important problems facingthe business.Our nature isto dig deeply into their details question assumptions understandthe smallest details,and drive towards the best possible solution using these insights.This makes us very effective in crafting new solutionsand operating in ambiguous circumstances.
Collaborate with kindness . We are exceptionally low ego,and treat each otherwith respect compassion,and humility.We hold one anotherto high standards,but do so while being deeply committedto each other's wellbeing.We investin each other's growth,and are willingto engagein difficult conversationsand deliver direct constructive feedback when necessary.
Be resourcefuland resilient . We figure out how tomake things work,and howto accomplishour goals regardlessof what standsin the way.We're keen to confront challenges together through proactive planningandscrappy methods.When things go wrong,we learn quicklyfromour missteps adaptour approach,and push forward.

COMPENSATION AND BENEFITS To build aworld-class team Kingdom is transparentand generouswithour compensation package.We anchor cash salary above market-rate compensationfor your role,and go aboveand beyondwith equity stock options as we want everyoneto be alignedwithand benefitfromour long-term success. For this position,we are most actively considering candidates atthe Senior Scientist level (PhD with ~1-3 years of post-PhD experience; cash salary range: $132.5K-$160K).This does not include stock options which we’ll discuss duringthe interview process. Kingdom additionally offers an excellent benefits package including: -100% fully-covered,best-in-class medical vision,and dental insurance for yourself(and95% for your spouse/family) -Generousand flexible PTO,in additionto13 company-wide holidays -Full commuter coverage -Fully stocked kitchen with fruits,s nacks,and beverages + weekly team lunches -12-weeks fully-paid parental leave -401k programwith minimal fees