Technology Development Scientist

Responsibilities

• Develop diagnostic methods to detect epigenetic signatures on circulating tumor DNA in human plasma samples
• Lead team to plan, design, and execute key technology development and testing
• Support in designing and executing guardbanding experiments for protocol formulation
• Lead data analysis and technical troubleshootings in internal meetings
• Author technical reports, SOPs, and technology transfer documents
• Contribute to scientific documentation of patent applications and subsequent internal and external presentation and/or publication of new technologies
• Train and oversee junior colleagues with respect to lab activities

Qualifications

• Ph.D in molecular biology, biochemistry, biotechnology, or related fields
• Previous experience with PCR assay development and molecular diagnostics
• Previous experience with DNA methylation analysis techniques such as qMSP, EM-Seq, and WGBS
• Excellent communication, presentation, and data analysis skills
• Strong desire to learn new techniques, willingness to work collaboratively as part of a team, and be productive in a fast-paced start-up environment

Recommended

• PhD with 1+ years of industry or relevant experience in process development
• Experience with NGS assay protocols including library preparation, target enrichment, and sequencing
• Experience with whole genome amplification (WGA) and isothermal amplification techniques
• Knowledge of statistical design of experiments, as well as data analysis using JMP or other statistical package is desired

Company Values (relevant context)

• Boldness - We take courageous stances to explore new scientific and clinical challenges.
• Excellence - We constantly push ourselves to deliver more value and impact.
• Integrity - We hold ourselves and our partners to the highest ethical and operational standards to ensure safety of patients.
• Collaboration - We leverage diversity of thought and multi-disciplinary mindsets.